//SYSIN DD *
If you compare a BI value to a decimal number (22), the BI value is interpreted as a binary number, so a value of '22' in the record is interpreted as its binary value of X'F2F2' = 62194. If you compare a BI value to a character constant ('22'), the BI value is interpreted as a character value, so a value of '22' in the record is interpreted as '22'. Thus 21,2,BI,GE,22 will not do what you want, but 21,2,BI,GE,C'22' will.
Alternatively you can treat the '22' as a ZD value of 22 and compare it to a decimal constant of 22, so 21,2,ZD,GE,22 will do what you want.
Note that using CH works fine as long as the numbers in the record use F as the sign. ZD works regardless of what's used as the sign (e.g. F, C or D).